Endocrine Abstracts

Objective: The tumor suppressor gene methylation lead to gene silencing, it plays an important role in thyroid tumor occurrence and development. This study examined the tumor suppressor gene (PTEN, RASSF1A, DAPK, RARβ2) DNA methylation and mRNA expression status in the peripheral blood of patients with nodular thyroid disease. Discuss its clinical significance. For the benign and malignant thyroid nodules early identification of molecular diagnosis is based.<p class="...

The defining feature of endometriosis is that endometrial tissues are deposited and grown onto sites outside of the uterine cavity. The pathogenesis of endometriosis, however, remains controversial despite extensive research. Since the endometriosis has been known as an estrogen-dependent inflammatory disease, the alterations in estrogen-mediated cellular signaling play an essential role in the pathogenesis of endometriosis. In addition to higher estrogen receptor (ER)β l...